Are Both Psychological and Physical Dimensions in Health-Related Quality of Life Associated with Mortality in Hemodialysis Patients: A 7-Year Taiwan Cohort Study

Yu-Sen Peng   Chih-Kang Chiang   Kung-Yu Hung   Chung-Hsin Chang
Chien-Yu Lin   Chwei-Shiun Yang   Tzen-Wen Chen   Ching-Chih Hsia
Da-Lung Chen   Wen-Ding Hsu   Chao-Fu Chang   Kwan-Dun Wu
Ru-Ping Lin   Tun-Jun Tsai   Wang-Yu Chen


Psychological depression and physical disability are closely correlated in hemodialysis patients. A retrospective cohort study was conducted to examine the independent association of physical and psychological functioning with mortality in a hemodialysis cohort

in Taiwan.Methods
A total of 888 stable hemodialysis patients were included. Patients completed two questionnaires: the 36 item Short Form Health Survey Questionnaire (SF-36,Taiwan
Standard Version 1.0) and the Beck Depression Inventory(BDI, Chinese Version). Mortality outcomes were recorded for a seven-year follow-up period. Results: There were 303 deaths recorded. BDI scores were inversely related to all health-related quality of life (HRQoL) domains (p ! 0.001). In the Cox-proportional hazard model, only poor physical dimension of HRQoL was independently associated with??higher mortality. Conclusion: Poor physical dimension in HRQoL is a strong predictor of mortality among hemodialysis patients in Taiwan. Psychological depression is closely correlated with poor HRQoL but does not predict mortality.

QoL and survival